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Professor Serge Charpak researches the effect of sensory stimulation on cellular network activity within the olfactory bulb. The group uses 2-photon imaging in rodents to measure blood flow and partial oxygen pressure, and determine how this is affected by sensory stimuli. These imaging techniques can be coupled with electrophysiological recording to characterise neuronal activity. 


Key publications

Rungta et al. 2017 Light controls cerebral blood flow in naive animals. Nat commun 8:14191  PMID: 28139643

Publication link: www.ncbi.nlm.nih.gov/pubmed/?term=28139643

Lyons et al. 2016 Mapping oxygen concentration in the awake mouse brain. ELife 5. pii:e12024 PMID: 26836304

Publication link: www.ncbi.nlm.nih.gov/pubmed/?term=26836304%5Buid%5D


Related links

Professor Serge Charpak profile at INSERM website

INSERM, Paris (Charpak)