APOE Webinar - Thursday 14th May 2020
Perivascular Spaces in Small vessel Disease Research Network would like to invite anyone to attend a webinar organised by the Cure Alzheimer's Fund. The main topic is focused on apolipoprotein E (APOE), blood–brain barrier dysfunction and cognitive decline. The webinar will take place on Thursday, 14th of May 2020.
Please note that the event sessions will take place at EDT local time.
Zoom access information
https://us02web.zoom.us/j/89468515435?pwd=RlI1cGVULzg3N28rSlFmcys2OHJQdz09
Password: CureAlz
| iPhone one-tap: | US: +16465588656,,89468515435#,,1#,911839# or +13017158592,,89468515435#,,1#,911839# |
| Telephone |
Callers will not be able to submit questions because the Q&A function requires a computer Dial (for higher quality, dial a number based on your current location): US: +1 646 558 8656 or +1 301 715 8592 or +1 312 626 6799 or +1 669 900 9128 or +1 253 215 8782 or +1 346 248 7799 Webinar ID: 894 6851 5435 Password: 911839 |
International numbers available: https://us02web.zoom.us/u/kAqxKQEbo
Event Schedule (please note these are project titles and talk topics may be more expansive):
12:45 – 12:55pm
Meg Smith (CureAlz)
Welcome
12:55 – 1:15pm
Christian Pike, Ph.D. (USC), and Caleb Finch, Ph.D. (USC)
Interactions among TREM2, APOE, and sex
1:15 – 1:35pm
Jean-Pierre Roussarie, Ph.D. (Rockefeller)
Fleming APOE Consortium: Regulation by APOE of selective neuronal vulnerability to Alzheimer’s
1:35 – 1:55pm
Oleg Butovsky, Ph.D. (Brigham and Women’s Hospital)
Fleming APOE Consortium: The role of APOE in microglia regulation in neurodegeneration
1:55 – 2:00pm Break
2:00 – 2:20pm
Berislav Zlokovic, M.D., Ph.D. (USC)
Molecular Signatures of APOE-Mediated Blood-Brain Barrier Dysfunction Causing Neuronal and Synaptic Dysfunction
2:20 – 2:40pm
Randall Bateman, M.D. (WUSTL)
Fleming APOE Consortium: Assessing the added diagnostic value of peripheral ApoE protein levels in current blood-based biomarker assays for CNS amyloidosis
2:40 – 3:00pm
David Holtzman, M.D. (WUSTL)
Fleming APOE Consortium: Understanding the effect of apoE on tau-mediated neurodegeneration
3:00 – 3:20pm
Daniel Laskowitz, M.D., M.H.S. (Duke)
A novel apoE mimetic therapeutic peptide CN-105 attenuates AD pathology and improves functional outcomes in a murine model of Alzheimer’s disease
3:20 – 3:40pm
Cheryl Wellington, Ph.D. (UBC)
Fleming APOE Consortium: Toward developing high density lipoprotein enriched in apolipoprotein E as a potential biomarker and therapeutic targeting vascular contributions to Alzheimer’s disease
3:40 – 4:00pm
Guojun Bu, Ph.D. (Mayo Jacksonville)
Fleming APOE Consortium: Counteracting Pathogenic Events in AD with Peripheral or Central ApoE
4:00 – 4:30pm
Li-Huei Tsai, Ph.D. (MIT), and Kellis, Manolis, Ph.D. (MIT)
Collaboration to Infer Regulatory Circuits and to Uncover Innovative Therapeutic Strategies