Dr Joel Ramirez
Dr Ramirez is a research associate under the Hurvitz Brain Sciences Program at the Sunnybrook Health Sciences Centre. He is currently involved with the analyses of several ongoing clinical trials such as the Sunnybrook Dementia Study, the Ontario Neurodegenerative Disease Research Initiative, the Canadian Atherosclerosis Imaging Network (CAIN), and the Medical Imaging Trials Network of Canada. The focus of his work is to understand how MRI-visible perivascular spaces and sleep fragmentation contribute to our understanding of the glymphatic system and brain clearance dysfunction. Additional work includes examining cholinergic hyperintensities in stroke and Alzheimer’s, developing tools to quantify enlarged perivascular spaces and cerebral microbleeds in amyloid angiopathy, examining cortical thinning in neurodegenerative disease, and examining white matter structural integrity using diffusion tensor imaging.
“My research focuses on the use of neuroimaging to examine the overlap between cerebrovascular disease, stroke, Alzheimer’s disease and associated dementias. More specifically, my work involves the systematic evaluation of neurovascular and neurodegenerative imaging biomarkers, with the goal of improving clinical diagnostic technologies and their potential use for future disease modifying therapeutics.”